Personnages principaux

Alan Thicke - Jason Roland Seaver

Joanna Kerns - Margaret Kathrine Seaver (Maggie Seaver) (Malone)

Kirk Cameron - Michael Aaron Seaver (Mike)

Victor DiMattia - Mike Seaver

Hunter Cope - Mike Seaver

Adam Teitlebaum - Mike Seaver

Tracey Gold - Carol Ann Seaver (Carol )

Elizabeth Ward - Carol Seaver (Episode pilot)

Judith Barsi - Carol Seaver

Jeremy Miller - Benjamin Hubert Horatio Humphrey Seaver (Ben)

Ashley Johnson - Christine Ellen Seaver (Chrissy)

Kristen & Kelsey Dohring - Chrissy Seaver

Khrystyne Haje - Chrissy Seaver

Leonardo DiCaprio - Luke Brower (Saison 7)

Membres de la famille

Gordon Jump - Ed Malone

Betty McGuire - Kate Malone

Jane Powell - Irma Overmier

Robert Rockwell - Wally Overmier

Amis et voisins

Richard Marion - Silvester Stabone

Ruth Silveria - Madame Stabone

Michael Kenworthy - Kris Koosman

Michael McManus - Buddy Koosman

Karla Tamburrelli - Jodi Creedmore

Asher Metchik - Max Creedmore

Amis et collègues de Maggie

Deborah White - Susan

Ken Tigar - Mr. Sid Sidlevich

Pamela Brull - Thelma

Peter Jurasik - Doug Stanton

Ami(es) et collègues de Mike

Andrew Koening - Richard Milhaus Stabone (Boner)

Jarrett Lennon - Richard Milhaus Stabone (Boner)

K.C. Martel - Edward Cornelius Zeff (Eddie)

Chelsea Noble - Kate MacDonnell

Julie McCullough - Julie Lynn Costello

Melissa Young - Tina Louise

Carmen Filpi - Fred the beggar

Gary Grubbs - George Brower

Tony Hablian - Jose Nuñez

Ami(es) et collègues de Carol

Christopher Burgard - Dwight Haliburton

Kevin Wixted - Bobby Winett

Matthew Perry - Sandy Callison

Lisa Capps - Debbie

Rachel Jacobs - Shelley

Evan Arnold - Richie

Robert Benedette - M. Ike Scoffengerio

Shawn Modrell - Brianne Miller

Ami(es) de Ben

Jamie Abbott - Bernard Sullivan (Stinky)

Jodi Peterson - Laura Lynn

Kenny Morrison - Vito Paducci

Jason Horst - Gary

Shavar Ross - Kenny

Michael Cudlitz - Chucksteak

Hilary Swank - Sasha Serotsky

Profs et principales

Sam Anderson - Principal Willis Dewitt

Fred Applegate - Principal Francis Tedesco

Patrika Darbo - Estelle McGillicuty

Bill Kirchenbauer - Coach Graham Lubbock

Steeve Arlen - Profeseur Peeter Thorne

Apparitions spéciales

Jerry Vale

Brian Austin Green - "Ben's Rap Group" #134

Jennie Garth - Denise "Ben and Mike's Excellent Adventure" #105.

Brad Pitt - Jeff "Who's Zoomin' Who?" #53 et Jonathon Keith "Feet of Clay" #84.

Hank Azaria - Steve Stevenson "New Deal (2)" #101.

Andrea Barber - Rhonda Green "Ben's Sure Thing" #123.

Alan Hale Jr. - Le chauffeur de taxi "This is Your Life" #54.

James Callahan - Oncle Bob "Extra Lap" #22.

Earl Boen - Dr. Marlen "Standarized Test" #11.

Kelly Ann Hu - Melia "Aloha (1)" #45, "Aloha (2)" #46 et "Great Expectations" #62.

Danny Cooksey - Le nouveau Ben "This is Your Life" #54.

Johnny Dark - Wailin' Wailer "Dance Fever (1)" #63 ,"Dance Fever (2)" #64 et Cousin Larry "Anniversary from hell" #85 et Moe Green "Ben's Sure Thing" #123.

Holly Fields - Courtney Preston "Mike the Director" #115.

Tracy Wells - Marlene "Carol's Papers" #98.

Candace Cameron (Soeur de Kirk) Jenny Foster.

Robert Cameron (Père de Kirk) Mike "All the World is a Stage" #137.

Robin Thicke (Fils d'Alan) Ralph "Ben and Mike's Excellent Adventure" #105.

Ashley Kerns (Fille de Joanna) fille de Joanna "Meet the Seavers" #139 et Crystal "Call of the Wild" #156.

Jessie Gold (Soeur de Tracey) Judith "Daddy Mike" #122.